Release of TNF-alpha during stent implantation into saphenous vein aortocoronary bypass grafts and its relation to plaque extrusion and restenosis.

@article{Bse2007ReleaseOT,
  title={Release of TNF-alpha during stent implantation into saphenous vein aortocoronary bypass grafts and its relation to plaque extrusion and restenosis.},
  author={Dirk B{\"o}se and Kirsten Leineweber and Thomas Friedrich Michael Konorza and Andreas Zahn and Martina Broecker-Preuss and Klaus Mann and Michael Haude and R. Erbel and Gerd Heusch},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2007},
  volume={292 5},
  pages={H2295-9}
}
The reduction in plaque volume during stent implantation is associated with the release of particulate debris and plaque-derived soluble substances. We studied the potential release of the proinflammatory cytokine TNF-alpha into the coronary circulation and whether such release is related to the reduction in plaque volume and, possibly, a predictor for restenosis. In 18 male patients (n = 24 stents) with severe stenosis in a saphenous vein aortocoronary bypass graft (SVG), we used a distal… CONTINUE READING

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