Release of Soluble E-Selectin from Activated Endothelial Cells upon Apoptosis

Abstract

Circulating soluble E-selectin is increased in diseases associated with endothelial apoptosis such as sepsis and acute respiratory distress syndrome. We investigated the mechanism by which endothelial cell (EC) apoptosis may promote soluble E-selectin release. We found that serum deprivation of EC caused apoptosis, yet it did not induce E-selectin EC… (More)
DOI: 10.1007/s00408-005-2589-5

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