Release kinetics of circulating muscle-enriched microRNAs in patients undergoing transcoronary ablation of septal hypertrophy.

@article{Liebetrau2013ReleaseKO,
  title={Release kinetics of circulating muscle-enriched microRNAs in patients undergoing transcoronary ablation of septal hypertrophy.},
  author={Christoph Liebetrau and Helge Moellmann and Oliver D{\"o}rr and Sebastian Szardien and Christian Troidl and Matthias Willmer and Sandra Voss and Luise Gaede and Johannes Rixe and Andreas Rolf and C. W. Hamm and Holger M. Nef},
  journal={Journal of the American College of Cardiology},
  year={2013},
  volume={62 11},
  pages={992-8}
}
OBJECTIVES This study sought to evaluate exact release kinetics of microRNAs (miRNAs) in acute myocardial infarction (AMI). BACKGROUND miRNAs may be useful as novel biomarkers in patients with cardiovascular disease, although it is difficult to establish the detailed release kinetics of miRNAs in patients with AMI. METHODS We analyzed the release kinetics of circulating cardiac-specific (miR-21, miR-208a) and muscle-enriched (miR-1, miR-133a) miRNAs using the TaqMan polymerase chain… CONTINUE READING

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