Release kinetics of actives from chewing gums into saliva monitored by direct analysis in real time mass spectrometry.


Direct analysis in real time mass spectrometry (DART-MS) was used to monitor the release kinetics of a taste-refreshing compound from chewing gums into the saliva of subjects. A new DART-MS sample probe was designed which was about four times more sensitive than the current benchmark probe. This decreased the impact of the dilution of the saliva samples… (More)
DOI: 10.1002/rcm.4500