Relaxin 2 is functional at the ocular surface and promotes corneal wound healing.

@article{Hampel2012Relaxin2I,
  title={Relaxin 2 is functional at the ocular surface and promotes corneal wound healing.},
  author={Ulrike Hampel and Thomas Klonisch and Eugenia Makrantonaki and Saadettin Sel and Ute Schulze and Fabian Garreis and Holger Seltmann and C C Zouboulis and Friedrich Paulsen},
  journal={Investigative ophthalmology & visual science},
  year={2012},
  volume={53 12},
  pages={7780-90}
}
PURPOSE We aimed to determine if the insulin-like peptide hormone relaxin 2 (RLN2) is expressed at the ocular surface and in tears and if RLN2 influences wound healing at the ocular surface, which is associated with extracellular matrix (ECM) remodeling. METHODS We analyzed transcript levels of human RLN2 and its cognate relaxin-like receptors RXFP1 and… CONTINUE READING