Relaxation of human placental arteries and veins by ATP-sensitive potassium channel openers.

@article{Jewsbury2007RelaxationOH,
  title={Relaxation of human placental arteries and veins by ATP-sensitive potassium channel openers.},
  author={Sally Jewsbury and Philip N. Baker and Mark Wareing},
  journal={European journal of clinical investigation},
  year={2007},
  volume={37 1},
  pages={65-72}
}
BACKGROUND Adenosine triphosphate (ATP)-sensitive potassium channels (K(ATP)) are important modulators of vascular tone. Preliminary data from our laboratory suggests that K(ATP) channels are expressed in the fetoplacental vasculature where addition of pinacidil, a specific K(ATP) opener, promotes relaxation. We aimed to assess the effects of KRN2391 and… CONTINUE READING