Corpus ID: 226887821

Relaxant effects of Peperomia hispidula (Sw.) A. dietr. on isolated rat tracheal rings

  title={Relaxant effects of Peperomia hispidula (Sw.) A. dietr. on isolated rat tracheal rings},
  author={Jes{\'u}s Arrieta and Yaraset L{\'o}pez-Lorenzo and Mayra Beatriz G{\'o}mez-Pati{\~n}o and Yolanda S{\'a}nchez-Mendoza and Mar{\'i}a Elena S{\'a}nchez-Mendoza},
  journal={Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants},
Peperomia hispidula (Sw.) A. Dietr. is used in Mexican traditional medicine for treating respiratory illnesses such as asthma. The latter disorder results from an excessive and inappropriate constriction of airway smooth muscle. The aim of the present study was to evaluate the relaxant activity of P. hispidula on isolated rat tracheal rings contracted with carbachol. The methyleugenol was identified as the main active constituent in the dichloromethane extract. To explore the possible mechanism… Expand
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