Relative time-profiles for free radical trapping, coronary flow, enzyme leakage, arrhythmias, and function during myocardial reperfusion.

A new finding is the discrimination between vascular radical concentration and rate of myocardial radical formation to investigate the pathogenic role of free radicals for the heart. For that purpose, the perfusate radical concentration (U/ml) and the rate of myocardial radical formation (U/min) were determined (using the ESR spin trap technique), and were… CONTINUE READING