Relative stereochemical determination and synthesis of the C17-C25 δ-lactone fragment of hemicalide.

Abstract

Hemicalide is a novel marine metabolite polyketide distinguished by a unique mechanism of action. Because of insufficient quantities of purified material, this natural product has evaded complete stereochemical assignments. Recently, we have determined the relative stereochemistry of the C8-C13 hexad by synthesizing the C1-C13 fragment. Presently, we report… (More)
DOI: 10.1021/jo302440a

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Cite this paper

@article{Fleury2013RelativeSD, title={Relative stereochemical determination and synthesis of the C17-C25 δ-lactone fragment of hemicalide.}, author={Etienne Fleury and Geoffroy Sorin and E. Prost and Ange Pancrazi and François Sautel and Georges Massiot and Marie-Isabelle Lannou and Janick Ardisson}, journal={The Journal of organic chemistry}, year={2013}, volume={78 3}, pages={855-64} }