Relative predispositional effects and mode of inheritance of HLA-DRB1 alleles among community-based Caucasian females with rheumatoid arthritis.

@article{Mu1998RelativePE,
  title={Relative predispositional effects and mode of inheritance of HLA-DRB1 alleles among community-based Caucasian females with rheumatoid arthritis.},
  author={Hua Mu and Mary Claire King and Lindsey A. Criswell},
  journal={Genetic epidemiology},
  year={1998},
  volume={15 2},
  pages={123-34}
}
Multiple HLA-DRB1 alleles encoding a shared epitope (SE) at amino acid positions 70-74 are associated with susceptibility to rheumatoid arthritis (RA). However, the nature of the association and the mode of inheritance differ depending upon the source of RA patients and laboratory methodology. We studied the relative predispositional effects (RPE) and mode… CONTINUE READING