Relative impact of respiratory muscle activity on tidal flow and end expiratory volume in healthy neonates

@article{Hutten2008RelativeIO,
  title={Relative impact of respiratory muscle activity on tidal flow and end expiratory volume in healthy neonates},
  author={Gerard J Hutten and Leo A. van Eykern and Philipp Latzin and Manuela Kyburz and Wim M. C. van Aalderen and Urs Frey},
  journal={Pediatric Pulmonology},
  year={2008},
  volume={43}
}
It has been suggested that infants dynamically regulate their tidal flow and end‐expiratory volume level. The interaction between muscle activity, flow and lung volume in spontaneously sleeping neonates is poorly studied, since it requires the assessment of transcutaneous electromyography of respiratory muscles (rEMG) in matched comparison to lung function measurements. 
View on Wiley
pure.uva.nl
38 Citations
Highly Influential Citations
1
Background Citations
12
Methods Citations
4
Results Citations
3

38 Citations

Citation Type

Citation Type

Transcutaneous monitoring of diaphragm activity as a measure of work of breathing in preterm infants
TLDR
The objective was to determine the correlation between conventional WOB measures and diaphragm activity, in preterm infants.
Respiratory Muscle Activity Related to Flow and Lung Volume in Preterm Infants Compared With Term Infants
TLDR
The temporal relationship of rEMG to flow and FRC and the loss of adaptive variability provide additional information on coping mechanisms in infants with CLD.
The Effect of Caffeine on Diaphragmatic Activity and Tidal Volume in Preterm Infants.
Nasal high flow in preterm infants: A dose‐finding study
To investigate the relationship between applied flows of nasal high flow (NHF) and physiological outcomes and work of breathing (WOB), to identify an optimal delivery flow which results in reduced…
Sources of variability in expiratory flow profiles during sleep in healthy young children
Challenging a paradigm: Positional changes in ventilation distribution are highly variable in healthy infants and children
Current understanding is that infants and children preferentially ventilate non‐dependent lungs, a reversal of that of adults, based on studies using krypton‐81m ventilation scanning. Participants in…
Respiratory muscle function in the newborn: a narrative review
Our aim was to summarise the current evidence and methods used to assess respiratory muscle function in the newborn, focusing on current and future potential clinical applications. The respiratory…
Tidal breathing flow volume profiles during sleep in wheezing infants measured by impedance pneumography.
TLDR
The study shows that TBFV indexes vary significantly because of sleep phase and asthma risk of the infant and that during REM the changes in TBfV indexes caused by airway obstruction are accentuated and better associated with lung function of the infants.
The relative impact of respiratory muscle activity on tidal flow and lung volume in infants
TLDR
This dissertation aims to provide a history of web exceptionalism from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which descriptions of “Web 2.0” began to circulate.
Diaphragmatic activity during weaning from respiratory support in preterm infants
TLDR
Weaning from nCPAP to LFNC leads to an increase in diaphragmatic activity measured by dEMG and is most prominent in preterm infants failing the weaning attempt, which might be a useful parameter to guide weaning from respiratory support in pre term infants.
...
1
2
3
4
...

References

SHOWING 1-10 OF 46 REFERENCES
Effects of technique and analytic conditions on tidal breathing flow volume loops in term neonates
The tidal breathing flow volume loop (TBFVL) may provide objective assessments of infant airway function. We examined whether infant biologic variability and technical limitations of commercial…
Respiratory muscle function in infants.
  • C. Gaultier
  • Medicine
    The European respiratory journal
  • 1995
TLDR
In newborns and infants a variety of respiratory disorders lead to ventilatory failure, and measurement of airway pressures during crying may provide an index of respiratory muscle strength in infants.
Dynamic maintenance of end-expiratory lung volume in full-term infants.
  • P. Kosch, A. Stark
  • Medicine, Biology
    Journal of applied physiology: respiratory, environmental and exercise physiology
  • 1984
TLDR
It is proposed that while braking plays a major role in the early part of expiration, as long as the final portion of expiration is passive, the dynamic maintenance of EEV above Vr depends on the relative values of tau and TE.
Reflex control of expiratory duration in newborn infants.
TLDR
Findings in infants are consistent with an integrative neural mechanism that modulates TE in response to the accumulated VE history, including both EEV and rate of lung deflation.
Reflex control of inspiratory duration in newborn infants.
TLDR
Findings indicate that neural inspiratory timing in infants depends on magnitude of phasic volume change during inspiration, consistent with the hypothesis that termination of inspiration is accomplished by an "off-switch" mechanism and that inspired volume determines the level of vagally mediated inspiratory inhibition to trigger this mechanism.
Importance of inspiratory muscle tone in maintenance of FRC in the newborn.
TLDR
The results suggest that inspiratory muscle tone is a major determinant of FRC in the newborn.
Optimized temperature and deadspace correction improve analysis of multiple breath washout measurements by ultrasonic flowmeter in infants
TLDR
Assessment of lung volume and ventilation inhomogeneities with ultrasonic flowmeter and multiple breath washout has been used to provide important information about lung disease in infants to lead to analysis errors in infants with critically small tidal volume changes during breathing.
Diaphragm Electrical Activity During Expiration in Mechanically Ventilated Infants
TLDR
Findings confirm that the diaphragm remains partially active during expiration in intubated and mechanically ventilated infants and that removal of PEEP affects this tonic activity, which could have potential implications on the management of PEP inintubated infants.
Posterior cricoarytenoid and diaphragm activities during tidal breathing in neonates.
TLDR
It is concluded that braking mechanisms in infants interact with vagal reflex mechanisms that modulate respiratory cycle timing to influence both the dynamic maintenance of end-expiratory lung volume and ventilation.
Respiratory muscle activity in the assessment of bronchial responsiveness in asthmatic children.
TLDR
Increase in the electrical activity of the diaphragm and intercostal muscles in asthmatic children corresponds closely to a 20% fall in FEV1 induced by histamine challenge.
...
1
2
3
4
5
...