Relative impact of CD4+CD25+ regulatory T cells and tacrolimus on inhibition of T-cell proliferation in patients with atopic dermatitis.

@article{VukmanovicStejic2005RelativeIO,
  title={Relative impact of CD4+CD25+ regulatory T cells and tacrolimus on inhibition of T-cell proliferation in patients with atopic dermatitis.},
  author={Milica Vukmanovic-Stejic and Arthur J. McQuaid and Katherine E Birch and John R. Reed and Cheryl Macgregor and Malcolm H. A. Rustin and Arne N. Akbar},
  journal={The British journal of dermatology},
  year={2005},
  volume={153 4},
  pages={750-7}
}
BACKGROUND It has been established recently that CD4+CD25+ regulatory T cells (Tregs) play an important role in controlling various immune responses. Immunosuppressive drugs are often used to treat immune dysregulation but are frequently associated with undesirable side-effects. OBJECTIVES We examined the suppressive capacity of circulating Tregs in patients with atopic dermatitis (AD). Combined effects of Tregs and tacrolimus on the inhibition of T-cell proliferation in vitro were also… CONTINUE READING
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