Relative deficiency of arginine vasopressin in children after cardiopulmonary bypass*

@article{Mastropietro2010RelativeDO,
  title={Relative deficiency of arginine vasopressin in children after cardiopulmonary bypass*},
  author={Christopher W Mastropietro and Noreen F. Rossi and Jeff A. Clark and Haiping Chen and Henry Lane Walters and Ralph E. Delius and Mary W. Lieh-Lai and Ashok P. Sarnaik},
  journal={Critical Care Medicine},
  year={2010},
  volume={38},
  pages={2052-2058}
}
Objective:To describe changes in plasma arginine vasopress in concentration in children following cardiopulmonary bypass and determine whether, in some patients, plasma arginine vasopressin remains relatively low despite hemodynamic instability. Design:Prospective observational study. Setting:Pediatric intensive care unit at a tertiary care university hospital. Patients:One hundred twenty patients ≤18 yrs of age undergoing open heart surgery requiring cardiopulmonary bypass at Children's… Expand

Paper Mentions

Interventional Clinical Trial
This is an investigator initiated, prospective, single-center, double-blinded, randomized, placebo-controlled trial of post-operative low dose vasopressin infusions as an early… Expand
ConditionsCirculatory Perfusion Disorder, Congenital Heart Disease, Single-ventricle
InterventionDrug
Hyponatremia During Arginine Vasopressin Therapy in Children Following Cardiac Surgery
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  • Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
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TLDR
Clinicians should be aware of this association, monitor serum sodium values closely, and consider providing less free water to these patients before hyponatremia occurs, which occurred in nearly half of the infants and children receiving arginine vasopressin therapy in this study. Expand
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The initiation of Arginine Vasopressin in post-operative Norwood patients was temporally associated with an improvement in markers of perfusion including systolic blood pressure, urine output, lactate, and pH. Expand
Arginine vasopressin and paediatric cardiovascular surgery
Introduction Arginine vasopressin has become an important part of the armamentarium available to paediatric cardiac intensive care physicians managing complex infants and children recovering fromExpand
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