Relative Expression of OCT4, SOX2 and NANOG in Oral Squamous Cell Carcinoma Versus Adjacent Non- Tumor Tissue

  title={Relative Expression of OCT4, SOX2 and NANOG in Oral Squamous Cell Carcinoma Versus Adjacent Non- Tumor Tissue},
  author={Fereshteh Baghai Naini and Pouyan Amini Shakib and A. Abdollahi and M. Hodjat and H. Mohammadpour and Neda Kardouni Khoozestani},
  journal={Asian Pacific Journal of Cancer Prevention : APJCP},
  pages={1649 - 1654}
Objective: Oral squamous cell carcinoma (OSCC) accounts for over 90% of oral neoplasms. Finding molecular markers for predicting prognosis is a high priority. The core transcription factors, OCT4, SOX2, and NANOG that regulate embryonic stem cell pluripotency have been implicated in progression of various malignancies. The predictive value of these markers and their role in the development of OSCC is still controversial. In this study, we therefore evaluated their expression in OSCCs and… Expand


Association of OCT4, SOX2, and NANOG expression with oral squamous cell carcinoma progression.
  • T. Fu, I. Hsieh, +9 authors L. Ger
  • Biology, Medicine
  • Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • 2016
Expression of SOX2 in oral squamous cell carcinoma and the association with lymph node metastasis.
The expression profile of Oct4 and Sox2 in the carcinogenesis of oral mucosa.
Positive Correlations of Oct-4 and Nanog in Oral Cancer Stem-Like Cells and High-Grade Oral Squamous Cell Carcinoma
Comparative analysis of Oct4 in different histological subtypes of esophageal squamous cell carcinomas in different clinical conditions.
SOX2 expression correlates with lymph-node metastases and distant spread in right-sided colon cancer
The SOX17/miR-371-5p/SOX2 axis inhibits EMT, stem cell properties and metastasis in colorectal cancer