Relative Contribution of P5 and Hap Surface Proteins to Nontypable Haemophilus influenzae Interplay with the Host Upper and Lower Airways

@inproceedings{Euba2015RelativeCO,
  title={Relative Contribution of P5 and Hap Surface Proteins to Nontypable Haemophilus influenzae Interplay with the Host Upper and Lower Airways},
  author={Bego{\~n}a Euba and Javier Moleres and Cristina Viadas and Ruiz De Los Mozos Igor and Jaione Valle and Jos{\'e} Antonio Bengoechea and J. Gonz{\'a}lez Garmendia},
  booktitle={PloS one},
  year={2015}
}
Nontypable Haemophilus influenzae (NTHi) is a major cause of opportunistic respiratory tract disease, and initiates infection by colonizing the nasopharynx. Bacterial surface proteins play determining roles in the NTHi-airways interplay, but their specific and relative contribution to colonization and infection of the respiratory tract has not been addressed comprehensively. In this study, we focused on the ompP5 and hap genes, present in all H. influenzae genome sequenced isolates, and… CONTINUE READING
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