Relationships of prostaglandin E and natural killer sensitivity to metastatic potential in murine mammary adenocarcinomas.

@article{Fulton1985RelationshipsOP,
  title={Relationships of prostaglandin E and natural killer sensitivity to metastatic potential in murine mammary adenocarcinomas.},
  author={Amy M. Fulton and Gloria H. Heppner},
  journal={Cancer research},
  year={1985},
  volume={45 10},
  pages={4779-84}
}
The levels of two prostaglandins (prostaglandins E and F) have been determined in a series of murine mammary lesions ranging from preneoplastic, hyperplastic alveolar nodules to highly metastatic adenocarcinomas. A highly positive correlation was seen between high levels of prostaglandin E and high tumorigenicity and metastatic potential. In addition, spontaneous metastasis of two highly metastatic tumors was partially inhibited by p.o. administration of indomethacin from the time of s.c. tumor… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 43 references

Inhibitory effect of prostaglandin F2.,on the growth of a hormone dependent rat mammary tumor

  • W. Jubiz, Frailey.J, J. B. Smith
  • Cancer Res.,
  • 1979
Highly Influential
6 Excerpts

Prostaglandins CANCER RESEARCH VOL

  • D.M.A. Watson, R. W. Kelly, R. A. Hawkins, W. R. Miller
  • on April
  • 1985
3 Excerpts

Indomethacin mediated inhibition of spon taneous metastasis of murine mammary tumors

  • A. M. Fulton, G. H. Heppner
  • Proc. Am. Assoc. Cancer Res.,
  • 1984
2 Excerpts

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