Relationships between total and unbound propofol in plasma and CSF during continuous drug infusion.

Abstract

BACKGROUND Propofol is one of the most frequently applied intravenous anesthetics. Although it has been used for a long period, its pharmacokinetics, especially central nervous system pharmacokinetics, are not fully recognized. OBJECTIVE Investigation of the relationships between total propofol concentration in blood, total propofol concentration in… (More)

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@article{Dawidowicz2004RelationshipsBT, title={Relationships between total and unbound propofol in plasma and CSF during continuous drug infusion.}, author={Andrzej Lech Dawidowicz and Rafal Kalityński and Anna Fijalkowska}, journal={Clinical neuropharmacology}, year={2004}, volume={27 3}, pages={129-32} }