Relationships between the physicochemical properties of an amphiphilic triblock copolymers/DNA complexes and their intramuscular transfection efficiency

@inproceedings{BelloRoufa2007RelationshipsBT,
  title={Relationships between the physicochemical properties of an amphiphilic triblock copolymers/DNA complexes and their intramuscular transfection efficiency},
  author={Mahajoub Bello-Roufa{\"i} and Olivier Lambert and Bruno Pitard},
  booktitle={Nucleic acids research},
  year={2007}
}
Poly(ethyleneoxide)-poly(propyleneoxide)-poly(ethyleneoxide) triblock copolymer (PEO-PPO-PEO) based plasmid delivery systems are increasingly drawing attention in the field of nonviral gene transfer because of their proven in vivo transfection capability. They result from the simple association of DNA molecules with uncharged polymers. We examined the… CONTINUE READING