Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography.

@article{Laruelle2003RelationshipsBR,
  title={Relationships between radiotracer properties and image quality in molecular imaging of the brain with positron emission tomography.},
  author={Marc Laruelle and Mark Slifstein and Yiyun Huang},
  journal={Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging},
  year={2003},
  volume={5 6},
  pages={
          363-75
        }
}
In molecular imaging of the brain, many factors affect the reliability of the quantitative information that can be derived from the imaging process. This article discusses factors impacting on the imaging quality that are related to the radiotracer per se. Following a brief summary of key concepts in receptor quantification, a number of these factors are discussed, including selectivity, affinity, delivery, and lipophilicity. Concepts discussed in the theoretical section are then illustrated… CONTINUE READING
Highly Cited
This paper has 181 citations. REVIEW CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 74 extracted citations

A biomathematical modeling approach to central nervous system radioligand discovery and development.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine • 2009
View 4 Excerpts
Highly Influenced

181 Citations

0102030'06'09'12'15'18
Citations per Year
Semantic Scholar estimates that this publication has 181 citations based on the available data.

See our FAQ for additional information.