Relationships between gastrointestinal microbiota and blood group antigens.

  title={Relationships between gastrointestinal microbiota and blood group antigens.},
  author={Anuhya Gampa and Phillip A Engen and Rima M Shobar and Ece A. Mutlu},
  journal={Physiological genomics},
  volume={49 9},
FUT2 is a gene for a fucosyltransferase that encodes expression of ABO blood group antigens found on gastrointestinal mucosa and secretions. We hypothesized that the fecal microbiomes of healthy subjects, with blood group antigens A, B, and O, have differing compositions. We analyzed 33 fecal and blood specimens from healthy subjects for FUT2 genotype, and the fecal microbiome was determined by 454 pyrosequencing. Our data show that being a blood group secretor is associated with less diversity… CONTINUE READING
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