Relationships between common polymorphisms of adenosine triphosphate-binding cassette transporter A1 and high-density lipoprotein cholesterol and coronary heart disease in a population with type 2 diabetes mellitus.

@article{PorchayBaldrelli2009RelationshipsBC,
  title={Relationships between common polymorphisms of adenosine triphosphate-binding cassette transporter A1 and high-density lipoprotein cholesterol and coronary heart disease in a population with type 2 diabetes mellitus.},
  author={Isabelle Porchay-Bald{\'e}relli and Franck P{\'e}an and Nathalie Emery and Suliya Maimaitiming and Naima Bellili and Florence Travert and Kamel Mohammedi and Ronan Roussel and Michel Marre and Fr{\'e}d{\'e}ric Fumeron},
  journal={Metabolism: clinical and experimental},
  year={2009},
  volume={58 1},
  pages={74-9}
}
Patients with type 2 diabetes mellitus (T2D) have a high coronary risk partly because of low levels of high-density lipoprotein-cholesterol (HDL-C). The adenosine triphosphate-binding cassette transporter A1 (ABCA1) plays a key role in HDL metabolism. We studied the association of common single nucleotide polymorphisms (SNPs) in the ABCA1 gene with HDL-C levels and coronary risk in a cohort of subjects with T2D. We studied 5 SNPs: +69C>T, +378G>C, R219K, I883M, and R1587K. The C allele of +378G… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 24 extracted citations

Associations of the ABCA1 and LPL Gene Polymorphisms With Lipid Levels in a Hyperlipidemic Population.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis • 2018

Similar Papers

Loading similar papers…