Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia.

Abstract

Excitotoxicity and ischemia can result in oxidative stress after TBI. Female sex hormones are hypothesized to be neuroprotective after TBI by affecting multiple mechanisms of secondary injury, including oxidative damage, excitotoxicity and ischemia. Ca2+ mediated oxidative stress increases with age, and hypothermia is known to attenuate secondary injury… (More)

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Cite this paper

@article{Wagner2004RelationshipsBC, title={Relationships between cerebrospinal fluid markers of excitotoxicity, ischemia, and oxidative damage after severe TBI: the impact of gender, age, and hypothermia.}, author={Amy K Wagner and H{\"u}lya Bay{\^i}r and Dianxu Ren and Ava M. Puccio and Ross D. Zafonte and Patrick M Kochanek}, journal={Journal of neurotrauma}, year={2004}, volume={21 2}, pages={125-36} }