Relationships among electrophysiological findings and clinical status, heart function, and extent of DNA mutation in myotonic dystrophy.

@article{Lazarus1999RelationshipsAE,
  title={Relationships among electrophysiological findings and clinical status, heart function, and extent of DNA mutation in myotonic dystrophy.},
  author={Arnaud Lazarus and Jean Varin and Zine Ounnoughene and H{\'e}l{\`e}ne Radvanyi and Claudine Junien and Jo{\"e}l Coste and Pascal Lafor{\^e}t and Bruno Eymard and Henri Marc B{\'e}cane and S Pary Weber and Denis Duboc},
  journal={Circulation},
  year={1999},
  volume={99 8},
  pages={1041-6}
}
BACKGROUND Impulse-conduction abnormalities and arrhythmias are common in myotonic dystrophy (MD). This study was performed to determine whether a correlation exists between electrophysiological (EP) testing data and clinical status, heart function, or size of the DNA abnormality (cytosine-thymine-guanine sequence repeat). METHODS AND RESULTS Eighty-three MD patients underwent invasive EP studies prompted primarily by the presence of asymptomatic conduction abnormalities. AV conduction… CONTINUE READING