Relationships Between Choline Magnetic Resonance Spectroscopy, Apparent Diffusion Coefficient and Quantitative Histopathology in Human Glioma

@article{Gupta2000RelationshipsBC,
  title={Relationships Between Choline Magnetic Resonance Spectroscopy, Apparent Diffusion Coefficient and Quantitative Histopathology in Human Glioma},
  author={Rakesh Kumar Gupta and Timothy F. Cloughesy and Usna Sinha and Justine Garakian and Jorge Antonio Lazareff and G. F. Rubino and Lisa Rubino and Donald P. Becker and H V Vinters and Jeffry R. Alger},
  journal={Journal of Neuro-Oncology},
  year={2000},
  volume={50},
  pages={215-226}
}
This study sought to correlate quantitative presurgical proton magnetic resonance spectroscopic imaging (1H- MRSI) and diffusion imaging (DI) results with quantitative histopathological features of resected glioma tissue. The primary hypotheses were (1) glioma choline signal correlates with cell density, (2) glioma apparent diffusion coefficient (ADC) correlates inversely with cell density, (3) glioma choline signal correlates with cell proliferative index. Eighteen adult glioma patients were… CONTINUE READING

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