Relationship of urinary pseudouridine and 1-methyladenosine to activity of leukemia and lymphoma.

@article{Itoh1992RelationshipOU,
  title={Relationship of urinary pseudouridine and 1-methyladenosine to activity of leukemia and lymphoma.},
  author={Kunio Itoh and Tasuke Konno and Takao Sasaki and Shunji Ishiwata and Nobuhiro Ishida and M Misugaki},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1992},
  volume={206 3},
  pages={181-9}
}
Urinary levels of pseudouridine and 1-methyladenosine in patients with leukemia and lymphoma were measured by the inhibition ELISA using monoclonal antibodies to determine the correlation of nucleosides excretion with disease activity. Significantly elevated levels of these nucleosides were detected in patients with all types of disease tested. Seventy-seven percent (46/60) and 62% (37/62) of patients had elevated levels of pseudouridine and 1-methyladenosine above normal mean + 2S.D… CONTINUE READING

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