Relationship of transforming growth factor beta 1 to extracellular matrix and stromal infiltrates in invasive breast carcinoma.

@article{Walker1994RelationshipOT,
  title={Relationship of transforming growth factor beta 1 to extracellular matrix and stromal infiltrates in invasive breast carcinoma.},
  author={Rosemary A. Walker and Sheila J. Dearing and B P Gallacher},
  journal={British Journal of Cancer},
  year={1994},
  volume={69},
  pages={1160 - 1165}
}
Transforming growth factor beta (TGF-beta) comprises a group of multifunctional regulatory proteins, whose effects include stimulation of extracellular matrix formation and modification of immune function. The presence of TGF-beta 1 and TGF-beta 2 in invasive breast carcinomas has been determined and related to pathological features, the presence of fibronectin and tenascin and lymphocyte/macrophage infiltration, using immunohistochemistry. Differences were observed in the extent of reactivity… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 24 references

Transforming growth factorP isoforms in mammary neoplasia : more questions than answers

  • R. J. COFFEY
  • Hum . Pathol .
  • 1992
1 Excerpt

Identification of a novel transforming growth

  • M. J. SANDS, J. M. SMITH, A. FIELDS, A. B. ROBERTS, M. B. SPORN, D. A. MELTON
  • 1990

Identification of a novel transforming growth factorP ( TGFp 5 ) mRNA in Xenopus laevis

  • B. K. MCCUNE, B. R. MULLIN, L. T. MULLEN, M. B. SPORN
  • J . Biol . Chem .
  • 1990

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