Relationship of magnetic resonance imaging estimation of myocardial iron to left ventricular systolic and diastolic function in thalassemia.

@article{Leonardi2008RelationshipOM,
  title={Relationship of magnetic resonance imaging estimation of myocardial iron to left ventricular systolic and diastolic function in thalassemia.},
  author={Benedetta Leonardi and Renee E Margossian and Steven D. Colan and Andrew J. Powell},
  journal={JACC. Cardiovascular imaging},
  year={2008},
  volume={1 5},
  pages={572-8}
}
OBJECTIVES We sought to evaluate whether echocardiographic diastolic function indices correlate with myocardial iron and systolic function in patients with transfusion-dependent thalassemia (TDT) who are at risk for cardiomyopathy. BACKGROUND In thalassemia syndromes, there is an important clinical need to risk stratify patients for the development of iron-overload cardiomyopathy so that chelation therapy can be adjusted and cardiac morbidity averted. This purpose may be served by measuring… CONTINUE READING