Relationship of hepcidin with parasitemia and anemia among patients with uncomplicated Plasmodium falciparum malaria in Ghana.

@article{Howard2007RelationshipOH,
  title={Relationship of hepcidin with parasitemia and anemia among patients with uncomplicated Plasmodium falciparum malaria in Ghana.},
  author={Caitlin T Howard and Uri S. McKakpo and Isabella A. Quakyi and Kwabena Mante Bosompem and Ebenezer A. Addison and Kai Sun and David M Sullivan and Richard D. Semba},
  journal={The American journal of tropical medicine and hygiene},
  year={2007},
  volume={77 4},
  pages={623-6}
}
The pathogenesis of malarial anemia is incompletely understood. Hepcidin, a recently discovered peptide hormone, is a major regulator of iron metabolism and is thought to play a central role in the anemia of chronic inflammation. The specific aim of the study was to characterize the association between urinary hepcidin, hemoglobin, and parasitemia in 199 patients presenting for evaluation of Plasmodium falciparum malaria in Ghana. Urinary hepcidin was semi-quantitatively assessed using surface… CONTINUE READING