Relationship of functional and antigenic interleukin 6 to disease activity in inflammatory bowel disease.

@article{Hyams1993RelationshipOF,
  title={Relationship of functional and antigenic interleukin 6 to disease activity in inflammatory bowel disease.},
  author={Jeffrey S. Hyams and John E. Fitzgerald and William R. Treem and Nancy Wyzga and Donald L. Kreutzer},
  journal={Gastroenterology},
  year={1993},
  volume={104 5},
  pages={1285-92}
}
BACKGROUND Intestinal and peripheral blood mononuclear cell interleukin 6 (IL-6) production in inflammatory bowel disease might present an increased quantity of IL-6 into the systemic circulation. The aim of the present study was to examine the relationship of circulatory IL-6 to the clinical and laboratory expression of inflammatory bowel disease in children. METHODS Sera were obtained from 26 children with ulcerative colitis, 49 with Crohn's disease, and 29 control patients. Serum… CONTINUE READING
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