Relationship of food intake, body composition, and tumor growth to host metabolism in nongrowing mice with sarcoma.

@article{Lundholm1980RelationshipOF,
  title={Relationship of food intake, body composition, and tumor growth to host metabolism in nongrowing mice with sarcoma.},
  author={Kent G Lundholm and Staffan Edstr{\"o}m and Ingvar Karlberg and Lena Ekman and Tore Scherst{\'e}n},
  journal={Cancer research},
  year={1980},
  volume={40 7},
  pages={2516-22}
}
A methylcholanthrene-induced sarcoma was transplanted in adult weight-stable mice. The relationship between sponta neous food intake and tumor growth, body composition, and host metabolism was studied. Tumor-bearing animals decreased their spontaneous food intake gradually from the day when the tumor became palpable (5 to 7 days) until reaching 50 to 60% of their initial intake 7 to 8 days later. The body dry weight (including tumor) and the lipid content of the tumor-bearing animals decreased… CONTINUE READING