Relationship of emphysema and airway disease assessed by CT to exercise capacity in COPD.

@article{Diaz2010RelationshipOE,
  title={Relationship of emphysema and airway disease assessed by CT to exercise capacity in COPD.},
  author={Alejandro Diaz and Brian J. Bartholmai and Ra{\'u}l San Jos{\'e} Est{\'e}par and James C. Ross and Shin Matsuoka and Tsuneo Yamashiro and Hiroto Hatabu and John J. Reilly and Edwin K. Silverman and George R. Washko},
  journal={Respiratory medicine},
  year={2010},
  volume={104 8},
  pages={1145-51}
}
OBJECTIVE To assess the association of emphysema and airway disease assessed by volumetric computed tomography (CT) with exercise capacity in subjects with chronic obstructive pulmonary disease (COPD). METHODS We studied 93 subjects with COPD (Forced Expiratory Volume in 1 s [FEV(1)] %predicted mean +/- SD 57.1 +/- 24.3%, female gender = 40) enrolled in the Lung Tissue Research Consortium. Emphysema was defined as percentage of low attenuation areas less than a threshold of -950 Hounsfield… CONTINUE READING