Relationship of disease severity to decline on specific cognitive and functional measures in Alzheimer disease.

@article{Schmeidler1998RelationshipOD,
  title={Relationship of disease severity to decline on specific cognitive and functional measures in Alzheimer disease.},
  author={James Schmeidler and Richard C. Mohs and Muhammedullah Aryan},
  journal={Alzheimer disease and associated disorders},
  year={1998},
  volume={12 3},
  pages={146-51}
}
Previous studies have shown that the sensitivity of global cognitive and functional measures to change in Alzheimer disease is related to overall disease severity. The present study assessed the sensitivity to decline, over a 12-month interval, for individual items of the cognitive portion of the Alzheimer Disease Assessment Scale (ADAS-Cog), the Instrumental Activities of Daily Living Scale (IADLS), and the Physical Self-Maintenance Scale (PSMS). This study was conducted in an effort to… CONTINUE READING

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