Relationship of c-myc and erbB oncogene family gene aberrations and other selected factors to ex vivo chemosensitivity of ovarian cancer in the modified ATP-chemosensitivity assay.

@article{Vogt2000RelationshipOC,
  title={Relationship of c-myc and erbB oncogene family gene aberrations and other selected factors to ex vivo chemosensitivity of ovarian cancer in the modified ATP-chemosensitivity assay.},
  author={Ulf Vogt and Bogdan Falkiewicz and Krzysztof P Bielawski and Ulrich Bosse and Claus M. Schlotter},
  journal={Acta biochimica Polonica},
  year={2000},
  volume={47 1},
  pages={
          157-64
        }
}
A pilot study on relationships of selected molecular factors [erbB-1, erbB-2, erbB-3, and c-myc oncogene average gene copy numbers (AGCN); steroid receptors and pS2 gene expression; tumor cells' DNA values] to the ex vivo chemosensitivity of ovarian cancer in a modified adenosine triphosphate cell viability chemosensitivity assay (ATP-CVA), was performed. Despite the relatively small number of patients, numerous correlations among the factors tested were found. Nevertheless, only c-myc gene… CONTINUE READING

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