Relationship of NKG2C Copy Number with the Distribution of Distinct Cytomegalovirus-Induced Adaptive NK Cell Subsets.

@article{Muntasell2016RelationshipON,
  title={Relationship of NKG2C Copy Number with the Distribution of Distinct Cytomegalovirus-Induced Adaptive NK Cell Subsets.},
  author={Aura Muntasell and Aldi Pupuleku and Elisa Cisneros and Andrea V{\'e}lez Vera and Manuela Moraru and Carlos Vilches and Miguel L{\'o}pez-Botet},
  journal={Journal of immunology},
  year={2016},
  volume={196 9},
  pages={3818-27}
}
CD94/NKG2C and lack of FcεRγ (FcRγ) expression are considered markers of the adaptive NK cell response to human CMV (HCMV) infection. Despite the fact that FcRγ(-) and NKG2C(bright) NK cells share some phenotypic, epigenetic, and functional features, their relationship remains unclear. To address this issue, a systematic analysis of NKG2C(bright) and FcRγ expression was carried out in NK cells from a cohort of healthy young adults (n = 81) considering NKG2C copy number, previously related to… CONTINUE READING
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