Relationship between the proliferative capability of hepatocytes and the intrahepatic expression of hepatocyte growth factor and c-Met in the course of cirrhosis development in rats.

@article{Inoue2006RelationshipBT,
  title={Relationship between the proliferative capability of hepatocytes and the intrahepatic expression of hepatocyte growth factor and c-Met in the course of cirrhosis development in rats.},
  author={Hideyuki Inoue and Fumi Yokoyama and Yuko Kita and Hitoshi Yoshiji and Tatsuhiro Tsujimoto and Akihiro Deguchi and Seiji Nakai and Asahiro Morishita and Naohito Uchida and Tsutomu Masaki and Seishiro Watanabe and Shigeki Kuriyama},
  journal={International journal of molecular medicine},
  year={2006},
  volume={17 5},
  pages={857-64}
}
Liver cirrhosis is the fatal end stage of various chronic liver diseases. One of the most important causes of liver cirrhosis appears to be an impaired proliferative capability of hepatocytes caused by continuous hepatic damage. Hepatocyte growth factor (HGF) and its specific receptor, c-Met, play a pivotal role in hepatocyte proliferation. However, the relationship between the proliferative capability of hepatocytes and the intrahepatic expression of HGF and c-Met during the course of… CONTINUE READING
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Cell cycle of hepatocellular carcinoma

  • T Masaki, A Morishita, +4 authors S Kuriyama
  • Research Signpost
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