Relationship between the Number of Carbon Chains and the Antifungal Activity of 9-Straight Chain Alkylated Acridine Derivatives

@inproceedings{Yoshiya1999RelationshipBT,
  title={Relationship between the Number of Carbon Chains and the Antifungal Activity of 9-Straight Chain Alkylated Acridine Derivatives},
  author={Haruo Yoshiya and Akira Kitamura and Kuniharu Takahashi and Akiyoshi Torii and Kichinosuke Kamata and Tadashi Yonemitsu and Masashi Tashiro and Shuntaro Mataka},
  year={1999}
}
The entire series of 9-straight chain alkylated acridine derivatives which are acridine (1, C0) -9-n-octiylacridine (9, C8) except C0 were synthesized and C0 was purchased. The relationship between the number of carbon chains on 9-straight chain alkylated acridine derivatives and their antifungal activity toward Aspergillus niger at pH 3.7, 5.2 and 7.0 was investigated by the paper disc method. The degrees of the antifungal activity of the tested compounds were estimated in terms of both… CONTINUE READING

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