Relationship between the Expression of E-, N-cadherins and beta-catenin and Tumor Grade in Astrocytomas

@article{Utsuki2002RelationshipBT,
  title={Relationship between the Expression of E-, N-cadherins and beta-catenin and Tumor Grade in Astrocytomas},
  author={Satoshi Utsuki and Yuichi Sato and Hidehiro Oka and Benio Tsuchiya and Sachio Suzuki and Kiyotaka Fujii},
  journal={Journal of Neuro-Oncology},
  year={2002},
  volume={57},
  pages={187-192}
}
Cadherins are cell-surface glycoproteins that mediate Ca2+-dependent, homophilic cell–cell adhesion. The classical cadherins, E- and N-cadherins, connect to beta-catenin, the lining protein. There appears to be a relationship between their dysfunction and tumor invasion and metastasis. The aim of our study was to examine the possibility of a relationship… CONTINUE READING