Relationship between synovial fluid levels of glycosaminoglycans, hydroxyproline and general MMP activity and the presence and severity of articular cartilage change on the proximal articular surface of P1.

@article{Boom2005RelationshipBS,
  title={Relationship between synovial fluid levels of glycosaminoglycans, hydroxyproline and general MMP activity and the presence and severity of articular cartilage change on the proximal articular surface of P1.},
  author={Robin van den Boom and Mark R van der Harst and Harold Brommer and Pieter A. J. Brama and A. S. Barneveld and P R van Weeren and Jeroen DeGroot},
  journal={Equine veterinary journal},
  year={2005},
  volume={37 1},
  pages={
          19-25
        }
}
REASONS FOR PERFORMING STUDY Osteoarthritis (OA) is one of the most prevalent and disabling chronic conditions affecting horses and leads to degeneration of articular cartilage. Diagnosis is based on clinical signs in combination with radiography, which is relatively insensitive and provides only an indication of accumulated damage. Alternative methods, such as molecular markers, are therefore needed that can quantitatively, reliably and sensitively detect osteoarthritic changes in the joints… CONTINUE READING

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