Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy.

@article{Chun2011RelationshipBR,
  title={Relationship between residual plasma viremia and the size of HIV proviral DNA reservoirs in infected individuals receiving effective antiretroviral therapy.},
  author={Tae-Wook Chun and Danielle D Murray and Jesse S. Justement and Claire W. Hallahan and Susan Moir and Colin M. Kovacs and Anthony S Fauci},
  journal={The Journal of infectious diseases},
  year={2011},
  volume={204 1},
  pages={
          135-8
        }
}
Residual plasma viremia (<50 copies/mL) persists in certain human immunodeficiency virus (HIV)-infected individuals receiving antiretroviral therapy (ART); however, the relationship between the degree of residual plasma viremia, the size of HIV reservoirs, and the level of immune activation has not been delineated. Here, we demonstrate that residual plasma viremia correlates with the size of the CD4(+) T cell viral reservoir, but not with markers of immune activation, suggesting that… CONTINUE READING

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