Relationship between preoperative amiodarone treatment and complications observed during anaesthesia for valvular cardiac surgery
@article{Chassard1990RelationshipBP, title={Relationship between preoperative amiodarone treatment and complications observed during anaesthesia for valvular cardiac surgery}, author={Dominique Chassard and M. George and M P Guiraud and Jean Jacques Lehot and Olivier Bastien and Christiane Hercule and Jacques Villard and Suzanne Estanove}, journal={Canadian Journal of Anaesthesia}, year={1990}, volume={37}, pages={251-254} }
Two groups of ASA physical status class III and IV patients undergoing cardiac surgery were reviewed in an attempt to obtain more conclusive data concerning dangerous interactions between amiodarone and anaesthesia. The amiodarone group (Group 1, ten patients, cumulative dose 10 g) was compared with a control group (nine patients, Group 2). Amiodarone (A) and desethylamiodarone (NA) concentrations in plasma and myocardium were measured and haemodynamic and antiarrhythmic effects were analysed…
12 Citations
Preoperative Therapy with Amiodarone and the Incidence of Acute Organ Dysfunction After Cardiac Surgery
- MedicineAnesthesia and analgesia
- 1997
There was no evidence to support the practice of stopping amiodarone before cardiac surgery to avoid serious complications, and the requirement for inotropes and vasopressors and the incidence of nosocomial infections were related to the severity of the underlying cardiac disease.
Amiodarone and anaesthesia: concurrent therapy with ACE inhibitors — an additional cause for concern?
- MedicineCanadian journal of anaesthesia = Journal canadien d'anesthesie
- 1991
Two further cases of serious hypotension requiring massive doses of alpha-agonists which occurred in two consecutive patients receiving amiodarone undergoing cardiopulmonary bypass (CPB) are reported.
[Peri-operative management of amiodarone patients.].
- MedicineRevista brasileira de anestesiologia
- 2004
Amiodarone, although normally safe and effective, may present adverse effects, especially on cardiovascular system, during anesthetic-surgical procedures, possibly due to interactions between this drug and anesthetic agents mainly related to general anesthesia.
Manuseio Peri-Operatório do Paciente em Uso de Amiodarona * Peri-Operative Management of Amiodarone Patients
- Medicine
- 2004
Amiodarone, although normally safe and effective, may present adverse effects, especially on cardiovascular system, during anesthetic-surgical procedures, possibly due to interactions between this drug and anesthetic agents mainly related to general anesthesia.
An assessment of the safety of short-term amiodarone therapy in cardiac surgical patients with fentanyl-isoflurane anesthesia.
- MedicineAnesthesia and analgesia
- 1999
A prospective, randomized, double-blinded study to evaluate the hemodynamic effects of short-term amiodarone therapy during fentanyl-isoflurane anesthesia for open heart surgery found no increased risk of hemodynamic compromise among patients receiving a fentanyl-containing anesthesia regimen duringopen heart surgery.
Reduced cardiac reserve in amiodarone-treated pigs after cardiopulmonary bypass and cardioplegic arrest.
- MedicineJournal of the American College of Cardiology
- 1992
Cardiovascular Pharmacotherapeutic Considerations in Patients Undergoing Anesthesia
- Medicine, BiologyCardiology in review
- 2011
Current recommendations suggest that beta blockers, calcium channel blockers, amiodarone, and alpha2 agonists should be continued throughout the perioperative period, whereas angiotensin-converting enzyme inhibitors, angiotENSin II receptor blockers, and diuretics should be discontinued on the morning of surgery and resumed in the immediate postoperativeperiod, unless contraindicated.
Safety Considerations in the Use of Drug Combinations During General Anaesthesia
- Biology, MedicineDrug safety
- 1997
The most commonly employed technique for providing general anaesthesia uses a balanced approach, where different drugs are used to reach specific desired endpoints to permit a rapid onset of desirable operative conditions.
Intraoperative pulmonary edema in a patient being treated with amiodarone.
- MedicineAnesthesia and analgesia
- 1991
miodarone is a potent cardiac antidysrhythmic drug approved for the treatment of recurA rent life-threatening cardiac dysrhythmias, recurrent hemodynamically unstable ventricular 'tachycardia, and…
Postoperative arrhythmias and conduction disorders.
- MedicineThe Medical clinics of North America
- 2001
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