Relationship between plasma homocysteine, vitamin status and extracranial carotid-artery stenosis in the Framingham Study population.

@article{Selhub1996RelationshipBP,
  title={Relationship between plasma homocysteine, vitamin status and extracranial carotid-artery stenosis in the Framingham Study population.},
  author={Jacob S Selhub and Paul F Jacques and Andrew G. Bostom and Ralph B. D'Agostino and Peter W. F. Wilson and Albert J. Belanger and Daniel H. O'Leary and Philip A. Wolf and D. Rush and Ernst J. Schaefer and Irwin H. Rosenberg},
  journal={The Journal of nutrition},
  year={1996},
  volume={126 4 Suppl},
  pages={1258S-65S}
}
Recent studies demonstrated associations between occlusive vascular disease and hyperhomocysteinemia of both genetic and nutritional origin. In the present study we analyzed plasma samples from the 20th biannual examination of the Framingham Heart Study cohort to determine distribution of plasma homocysteine concentrations with emphasis on relationships to B vitamins and prevalence of carotid artery stenosis. Results showed that homocysteine exhibited strong inverse association with plasma… CONTINUE READING

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