Relationship between phosphoinositide kinase activities and protein tyrosine phosphorylation in plasma membranes from A431 cells.

@article{Payrastre1990RelationshipBP,
  title={Relationship between phosphoinositide kinase activities and protein tyrosine phosphorylation in plasma membranes from A431 cells.},
  author={Bernard Payrastre and Monique Plantavid and Monique Breton and Edmond M. Chambaz and Hugues Chap},
  journal={The Biochemical journal},
  year={1990},
  volume={272 3},
  pages={665-70}
}
Production of PtdIns(4)P and PtdIns(4,5)P2 by plasma-membrane preparations from A431 cells was selectively stimulated in a dose-dependent manner by epidermal growth factor (EGF) in the presence of Na3VO4. Na3VO4 itself mimicked this effect, which was overcome after treatment by a specific phosphotyrosyl phosphatase isolated from A431 cells. PtdIns and… CONTINUE READING