Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases

@inproceedings{Yilmaz2012RelationshipBP,
  title={Relationship between paraoxonase and homocysteine: crossroads of oxidative diseases},
  author={Necat Yilmaz},
  booktitle={Archives of medical science : AMS},
  year={2012}
}
Homocysteine (Hcy) is an accepted independent risk factor for several major pathologies including cardiovascular disease, birth defects, osteoporosis, Alzheimer's disease, and renal failure. Interestingly, many of the pathologies associated with homocysteine are also linked to oxidative stress. The enzyme paraoxonase (PON1) - so named because of its ability to hydrolyse the toxic metabolite of parathion, paraoxon - was also shown early after its identification to manifest arylesterase activity… CONTINUE READING

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