Relationship between obesity and foot pain and its association with fat mass, fat distribution, and muscle mass

  title={Relationship between obesity and foot pain and its association with fat mass, fat distribution, and muscle mass},
  author={Stephanie K. Tanamas and Anita E. Wluka and Patricia A. Berry and Hylton B. Menz and B Strauss and Miranda L. Davies-Tuck and Joseph Proietto and John B. Dixon and Graeme Jones and Flavia M. Cicuttini},
  journal={Arthritis Care \& Research},
To examine the relationship between obesity, body composition, and foot pain as assessed by the Manchester Foot Pain and Disability Index (MFPDI). 

Fat mass is a predictor of incident foot pain

A longitudinal study was conducted to examine the relationship between body composition and incident foot pain over 3 years and found increased BMI and fat mass have been linked only to foot pain prevalence.

Relationships Between Body Mass Index, Fat Mass, Muscle Mass, and Musculoskeletal Pain in Community Residents

To evaluate the relationships between fat mass, muscle mass, fat:muscle mass ratio, metabolic syndrome, and musculoskeletal pain in community residents, a large number of community residents are surveyed.

Associations Between Body Mass Index and Foot Joint Pain in Middle-Aged and Older Women: A Longitudinal Population-Based Cohort Study

To investigate the relationship between body mass index (BMI) and foot joint pain (FJP) over a 5‐year period in a community‐based cohort.

Association of Fat Mass and Adipokines With Foot Pain in a Community Cohort

To determine, first, if fat mass index (FMI) or fat‐free mass index (FFMI) and serum adipokines tumor necrosis factor (TNF) and interleukin‐6 (IL‐6) are associated with prevalent (stage 2) foot pain,

Associations Between Fat Mass and Multisite Pain: A Five‐Year Longitudinal Study

This study aimed to examine longitudinal associations between fat mass and MSP, and to explore the potential mechanisms of any associations.

Relationship Between Mental Health and Foot Pain

A 3‐year longitudinal study is conducted to examine the relationship between mental health and foot pain in a community‐based population.

Not just loading and age: the dynamics of osteoarthritis, obesity and inflammation

This work has shown that obesity is a causative factor in the development of OA, with increased weight being associated with early articular cartilage damage, well before symptoms develop.

Foot pain severity is associated with the ratio of visceral to subcutaneous fat mass, fat-mass index and depression in women

For women with foot pain, VAT/SAT, FMI and depression were associated with severity, and further work is needed to determine if a reduction in fat mass reduces the severity ofFoot pain, not body composition, was associated with prevalent foot pain.

Fat Mass Is Associated with Foot Pain in Men: The Geelong Osteoporosis Study

Findings complement those in studies that have mainly examined women, and provide further evidence for the relationship between obesity and foot pain, that fat mass is associated with foot pain in men.



Foot Pain and Disability in Older Persons: An Epidemiologic Survey

OBJECTIVE: To investigate the prevalence of foot pain in older people and its association with pathological conditions of the feet and with disability in basic and instrumental activities of daily

Musculoskeletal pain in obese children and adolescents

To determine whether bodyweight is associated with musculoskeletal pain within a population of obese children and adolescents, a large study of overweight and obese adolescents is conducted.

Foot Musculoskeletal Disorders, Pain, and Foot‐Related Functional Limitation in Older Persons

To examine whether common musculoskeletal disorders of feet are associated with pain and foot‐related functional limitation, a large number of patients with these disorders have had surgery.

The synovial fluid adiponectin-leptin ratio predicts pain with knee osteoarthritis

A greater A/L ratio was associated with less pain with severe knee OA and this metabolic pathway may represent a target for novel therapeutics.

The biomechanics of adiposity – structural and functional limitations of obesity and implications for movement

A better appreciation of the implications of increased levels of body weight and/or body fat on movement capabilities of the obese would provide an enhanced opportunity to offer more meaningful support in the prevention, treatment and management of the condition.

Fat flat frail feet: how does obesity affect the older foot

The purpose of this study was to determine the effects of obesity on foot structure and function, and the foot pain experienced by older adults, and whether these negative effects associated with childhood obesity persist in the elderly foot.

Obesity and quality of life: mediating effects of pain and comorbidities.

J-shaped associations between BMI and HRQL indices were observed and adding joint pain and obesity-related comorbidities into models attenuated BMI-HRQL associations.

Body composition phenotypes in pathways to obesity and the metabolic syndrome

Recent advances in concepts about body composition phenotypes and health risks are reviewed in the light of race/ethnic variability in metabolic susceptibility to obesity and the metabolic syndrome.

Does obesity influence foot structure and plantar pressure patterns in prepubescent children?

It is postulated that foot discomfort-associated structural changes and increased forefoot plantar pressures in the obese foot may hinder obese children from participating in physical activity and therefore warrants immediate further investigation.

The cross-sectional relationship between fortnightly exercise and knee cartilage properties in healthy adult women in midlife

These findings provide further support for a beneficial effect of regular exercise on diseases related to aging, and need to be confirmed longitudinally.