Relationship between neurometabolite derangement and neurocognitive dysfunction in systemic lupus erythematosus.

@article{Brooks1999RelationshipBN,
  title={Relationship between neurometabolite derangement and neurocognitive dysfunction in systemic lupus erythematosus.},
  author={William M. Brooks and Rex E. Jung and Corey Ford and E J Greinel and Wilmer L Sibbitt},
  journal={The Journal of rheumatology},
  year={1999},
  volume={26 1},
  pages={81-5}
}
OBJECTIVE To determine the relationship between neurochemical markers of brain injury and brain dysfunction associated with systemic lupus erythematosus (SLE). METHODS Patients with SLE (n = 12) were studied using magnetic resonance spectroscopic imaging at 1.5 Tesla to determine neurochemistry and a neurocognitive testing battery to determine brain dysfunction. N-acetylaspartate (NAA), creatine (Cre), and choline (Cho) concentrations were measured in white (WM) and gray (GM) matter and… CONTINUE READING
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