Relationship between neuroendocrine features and prognostic parameters in human prostate adenocarcinoma.

@article{Bollito2001RelationshipBN,
  title={Relationship between neuroendocrine features and prognostic parameters in human prostate adenocarcinoma.},
  author={Enrico Bollito and Alfredo Berruti and Maurizio Bellina and Alessandra Mosca and E. J. Leonardo and Roberto Tarabuzzi and Susanna Cappia and Mustafa Ari and Marco Tampellini and Domingos Fontana and Luciano Gubetta and Adeline Angeli and Luca Dogliotti},
  journal={Annals of oncology : official journal of the European Society for Medical Oncology},
  year={2001},
  volume={12 Suppl 2},
  pages={S159-64}
}
PURPOSE The biological behaviour of prostate cancer is highly variable and prediction by the commonly employed prognostic parameters is not sufficient. The concept of neuroendocrine (NE) differentiation in prostate adenocarcinoma has recently received increasing attention due to possible implications for prognosis and therapy. MATERIALS AND METHODS Core needle biopsies from 142 newly diagnosed patients were immunohistochemically examined for the coexistence of NE differentiation using an… CONTINUE READING