Relationship between multifunctional protein "clusterin" and Alzheimer disease.

  title={Relationship between multifunctional protein "clusterin" and Alzheimer disease.},
  author={Nam-Ho Choi-Miura and Tomiichiro Oda},
  journal={Neurobiology of aging},
  volume={17 5},
In the Alzheimer disease (AD) brain, senile plaques contain several proteins and cytokines, such as beta-amyloid protein (A beta), interleukin 1, transforming growth factor beta 1 (TGF beta 1), and apolipoprotein E, which may contribute to the process of neurodegeneration. Clusterin is also known to colocalize with A beta deposits in neuritic plaques… CONTINUE READING