Relationship between metabolic rate, free radicals, differentiation and aging: a unified theory.

@article{Sohal1985RelationshipBM,
  title={Relationship between metabolic rate, free radicals, differentiation and aging: a unified theory.},
  author={Rajindar S. Sohal and Robert G. Allen},
  journal={Basic life sciences},
  year={1985},
  volume={35},
  pages={75-104}
}
Metabolic rate is a major factor governing the rate of aging in both homeotherms and poikilotherms and is inversely related to life span. Homeotherms exhibit stable basal metabolic rates and species-specific life spans. Conversely, in poikilotherms, both basal metabolic rate and life span vary greatly. Metabolic potential (total energy consumed/g/life span) is a species-specific characteristic in Homoetherms and poikilotherms. Length of life is dependent upon the rate at which this fixed… CONTINUE READING