Relationship between magnesium and clinical biomarkers on inhibition of vascular calcification.

  title={Relationship between magnesium and clinical biomarkers on inhibition of vascular calcification.},
  author={Silvia Salem and Heike Bruck and Ferdinand Hermann Bahlmann and Mirjam E Peter and Jutta Passlick-Deetjen and Axel Kretschmer and Sonja Steppan and Michaela Volsek and Andreas Kribben and Marc Nierhaus and Vera Jankowski and Walter Zidek and Joachim Jankowski},
  journal={American journal of nephrology},
  volume={35 1},
BACKGROUND Arteriosclerosis and cardiovascular disease are strongly associated with vascular calcification. Hyperphosphatemia is an essential risk factor for increased vascular calcification. End-stage renal disease (ESRD) patients could serve as an in vivo model for accelerated calcification. This study focuses on the most likely protective effects of magnesium ion (Mg(2+)) on phosphate-induced vascular calcification ex vivo/in vitro. Furthermore, plasma Mg(2+) concentrations of ESRD and… CONTINUE READING
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