Relationship between host survival and the type of immune response in different organs during disseminated candidiasis

@article{Fei2008RelationshipBH,
  title={Relationship between host survival and the type of immune response in different organs during disseminated candidiasis},
  author={Cao Fei and Li Jiawen and Yan Xiaofeng and Wu Yanqing and Zhang Demei},
  journal={Journal of Huazhong University of Science and Technology [Medical Sciences]},
  year={2008},
  volume={25},
  pages={141-143}
}
To examine the relationship between host survival and the type of immune response in different organs during disseminated candidiasis, the murine model of disseminated candidiasis was established by injection withCandida albicans via tail vein. The survival time was observed for up to 60 days. And the expression levels of cytokines in the spleen and kidney, including IFN-γ and IL-4, were determined with RT-PCR. Our results showed that in the spleen, both non-fatal and fatal inoculum caused a… CONTINUE READING